Myocardial blood flow quantitation with the SPECT technique: Is it ready to be a substitute for PET myocardial blood flow quantitation?
نویسندگان
چکیده
منابع مشابه
Absolute quantitation of myocardial blood flow in human subjects with or without myocardial ischemia using dynamic flurpiridaz F 18 PET.
UNLABELLED Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of analyzing coronary artery disease (CAD) but subject to the various shortcomings of available radiotracers. Flurpiridaz F 18 is a novel PET radiotracer that exhibits properties of an ideal tracer. METHODS A new absolute perfusion quantitation method with flurpiridaz was developed, taking advantag...
متن کاملQuantitative Assessment of Regional Myocardial Blood Flow with Clinical SPECT
This article gives an overview of essential requirements and limitations in the quantitative assessment of regional myocardial perfusion or regional myocardial blood flow (rMBF) using existing clinical SPECT systems in clinical settings. One major requirement is the need for acquiring complete projection data without truncation. Attenuation and scatter are then prerequisites to reproduce quanti...
متن کاملMyocardial Blood Flow
We examined the ability of individual regions of the canine left ventricle to increase blood flow relative to baseline rates of perfusion. Regional coronary flow was measured by injecting radioactive microspheres over 90 seconds in seven anesthetized mongrel dogs. Preliminary experiments demonstrated a correlation between the regional distributions of blood flow during asphyxia and pharmacologi...
متن کاملMyocardial Blood Flow
Coronary sinus flow (CSF) was measured in seven patients with normal coronary arteries (group A) during intracoronary injections of 6 ml arterial blood, 6 ml blood from the coronary sinus, 3 and 6 ml isotonic saline, 3 and 6 ml hypertonic glucose, and 6 ml of a contrast agent (sodium metrizoate). In 10 patients with coronary artery disease (group B), CSF was measured after administration of 6 m...
متن کاملMyocardial Blood Flow
Current methods of measuring myocardial blood flow using 133xenon have failed to separate normals from patients with ischemic heart disease at rest. In the present study such a separation was attempted by utilizing pacing-induced tachycardia (PIT) to stress the myocardium. 133Xenon was injected into the left coronary artery to measure blood flow in 27 patients at rest and during pacing-induced ...
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ژورنال
عنوان ژورنال: Journal of Nuclear Cardiology
سال: 2021
ISSN: 1071-3581,1532-6551
DOI: 10.1007/s12350-021-02697-5